MAL-DPEG 8-TFP ESTER

Code: QBD10552-1000MG D2-231

Features and Benefits

MAL-dPEG®8-TFP ester is a heterobifunctional, linear crosslinking reagent containing a maleimide group on one end of the sing...


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€705.00 EACH
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Features and Benefits

MAL-dPEG®8-TFP ester is a heterobifunctional, linear crosslinking reagent containing a maleimide group on one end of the single molecular weight dPEG® spacer arm and an amine-reactive active ester on the other end. The maleimide group reacts readily and specifically with free sulfhydryl groups in aqueous media at pH 6.5-7.5. The 2,3,5,6-tetrafluorophenyl (TFP) ester is used widely in reactions with primary amines. The TFP-amine reactions can be carried out in aqueous or organic solvent. The dPEG® spacer is hydrophilic and non-immunogenic. Because it is a single molecular weight product, it gives the user precise spatial control. The dPEG® spacer also improves water solubility, decreases immunogenicity, and increases the hydrodynamic volume of the conjugate. The increased hydrodynamic volume results in longer serum half-life in vivo.

Legal Information

dPEG is a registered trademark of Quanta BioDesign

Products Protected under U.S. Patents # 7,888,536 B2

assay>90%
formsolid or viscous liquid
polymer architectureshape : linearfunctionality : heterobifunctional
reaction suitabilityreagent type: cross-linking reagentreactivity: amine reactive, reagent type: cross-linking reagentreactivity: thiol reactive
shipped inambient
SMILES stringO=C(OC1=C(F)C(F)=CC(F)=C1F)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O
storage temp.−20°C
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